Faculty Advisor

Camesano, Terri Anne

Faculty Advisor

Page, Raymond L.

Abstract

Blood coagulation is an important aspect of hemostasis in the human body. Under normal circumstances, the blood coagulates using two different pathways, the intrinsic and the extrinsic. The extrinsic pathway works to counteract trauma but may lead to stroke forming clots. Components for an assay were created so that an assay could be designed to test the functionality of the proteins involved in the clotting cascade: Tissue Factor, factor VII, and factor X when used in conjunction with Template Directed Assembly (TDA) on a nickel-nitriloacetic acid (Ni-NTA) derived liposome.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2012

Major

Biomedical Engineering

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemical Engineering

Advisor Department

Biomedical Engineering

Share

COinS