Faculty Advisor

Adams, David S.

Abstract

This project focuses on SARS coronavirus infection. Immunofluorescence microscopy was used to locate several factors that could help in investigating SARS pathology. The locations of two cytokines were investigated in relation to SARS CoV infected cells. Infected cells were also stained to determine their cell type. SARS CoV infected cells did not stain positive for macrophage or epithelial cell markers. SARS CoV infected cells were also not producing TGF-beta or TNF-alpha, two prominent cytokines involved with inflammation. These results will be used to design in vitro experiments to further examine SARS CoV infection.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2005

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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