Student Work

LOCALIZATION OF NICOTINIC RECEPTORS ON HAIR CELLS AND AFFERENTS OF THE TURTLE SEMICIRCULAR CANAL

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A distinct alpha9 nicotinic acetylcholine receptor (nAChR) may mediate the inhibition of type II hair cells in the turtle posterior crista. This project aims to localize these nAChRs in the hair cell layer with the use of commercial antibodies and fluorophore-conjugated nicotinic antagonists (e.g., alpha-bungarotoxin). An additional goal has been the optimization and development of protocols for this specific purpose. Identification and visualization of these nAChRs will provide greater insight into the complex neural pharmacology of the inner ear.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Contributors
Publisher
Identifier
  • E-project-102207-015235
Advisor
Year
  • 2007
Sponsor
Date created
  • 2007-10-22
Location
  • Galveston
Resource type
Major
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Last modified
  • 2023-09-19

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