Burdette, Shawn C
Caged complexes are metal ion chelators that release analytes when exposed to light of a specific wavelength. When irradiated, the complex undergoes a structural change that weakens the metal-ligand interaction and shifts the binding equilibrium to free metal ions. This chemistry is then studied and applied to biological research in areas such as metal ion homeostasis and metal-based neurotransmission. This project continued the research of photochemistry through the synthesis and characterization of carboxylic acid derivative ligands that can bind to various metals and create photocage complexes. The properties and photochemistry of the complexes were then analyzed and used to determine new ligand syntheses.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry