Faculty Advisor

Camesano, Terri Anne

Faculty Advisor

Rao, Reeta Prusty

Abstract

Candida albicans and Pseudomonas aeruginosa are 2 of the most common healthcare related diseases today. Candida is ranked the 4th most common cause of 46,000 healthcare associated bloodstream infections (CDC, 2013). Pseudomonas causes 51,000 infections in the bloodstream and at surgical sites (CDC, 2013). Due to their ability to form infectious biofilms on biotic/abiotic surfaces, they are rapidly becoming drug resistant. With few new drugs manufactured each year these infections pose serious public health threats. Filastatin is a small molecule that exhibits inhibitory properties. Growth phases of C. albicans and P. aeruginosa when exposed to Filastatin were examined. Results indicated that Filastatin does disrupt the initial growth of both C. albicans and P. aeruginosa.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2015

Major

Biology and Biotechnology

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemical Engineering

Advisor Department

Biology and Biotechnology

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