Student Work

Incorporating Filastatin into medical plastics to minimize nosocomial fungal infections

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Candida albicans commonly infect medically implanted devices. To combat C. albicans’ increasing resistance to current treatment methods, a preventative measure was developed by incorporating Filastatin into silicone catheters. Filastatin was shown to inhibit the adhesion of cells by constraining the development of hyphae that allow the cells to adhere to one another and to surfaces. Different drug incorporation methods were developed and tested to determine the best way to utilize Filastatin in order to inhibit C. albicans from adhering to silicone urinary catheters.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-042816-152414
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  • 2016
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  • 2016-04-28
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