Faculty Advisor

Sullivan, John M

Abstract

This study investigated the effects of stress and nicotine for ADHD and normal subjects. Rat models were used. Greater nicotine sensitization was hypothesized for the ADHD model compared to the control. It was further hypothesized that sensitization would be amplified when stress was coupled to nicotine for both models. The amplification is quantified by the increased locomotion and decreased sensitization rate. The results supported the first hypothesis, however, locomotion decreased with the coupled stimuli.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2006

Major

Biology and Biotechnology

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Mechanical Engineering

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