Faculty Advisor

Rulfs, Jill


This study reports trends in nosocomial ICU-associated blood stream infections (BSIs) in a tertiary care academic medical center for a ten year period. The rate of change for primary and secondary BSIs was determined, as well as the distribution of causative organisms and source subclass. Primary BSIs decreased by 85.0%; secondary BSIs decreased by 81.4%. The total BSI rate per 1000 patient days decreased from 5.67 to 0.98, an 82.8% decrease. Both S. aureus and S. not-aureus infections decreased by 97.3% and 89.7% respectively; other species decreased by 60-80%. This study demonstrates that the interventions, both technical and educational, direct and indirect, put into place during the study period were effective in greatly reducing hospital-acquired BSIs in the ICU setting.


Worcester Polytechnic Institute

Date Accepted

April 2015


Biology and Biotechnology

Project Type

Major Qualifying Project



Advisor Department

Biology and Biotechnology