Cell behavior is modulated by mechanical stimuli including mechanical stretch, substrate stiffness, and geometrical constraint. A method was developed to combine these mechanical stimuli for cell mechanotransduction studies. This involved the use of microcontact printing to constrain cell clusters on stretchable substrates of alterable stiffness. Additionally, fiducial markers were incorporated for analysis of cell traction forces during stretching.
Worcester Polytechnic Institute
Major Qualifying Project
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