Student Work

Developing a Method for Characterizing Mechanotransduction in Cell Clusters: Stretching Substrates with Alterable Stiffness

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Cell behavior is modulated by mechanical stimuli including mechanical stretch, substrate stiffness, and geometrical constraint. A method was developed to combine these mechanical stimuli for cell mechanotransduction studies. This involved the use of microcontact printing to constrain cell clusters on stretchable substrates of alterable stiffness. Additionally, fiducial markers were incorporated for analysis of cell traction forces during stretching.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-042617-233218
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Year
  • 2017
Date created
  • 2017-04-26
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