To better understand the relationship between cell growth and plant morphology, I conducted time- series microscopy of live moss plants. In order to do this, I developed a new growth plate which allows the moss plants to be kept alive, and imaged under a microscope, for an extended period of time. I also explored the parameter space of a moss growth computer simulation to see how effective the growth assay is. This is used to determine how well different mutant moss strains grow. Additionally, a K-nearest neighbors model was developed to be able to predict changes in cell structure of possible mutant plants. The time series microscopy, improved assay, and model will be used to predict how genetic changes that affect cell growth alter plant morphology.
Worcester Polytechnic Institute
Bioinformatics and Computational Biology
Major Qualifying Project
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Biology and Biotechnology