Faculty Advisor

Srinivasan, Jagan

Abstract

To understand the balance between “nature versus nurture”, we developed a paradigm to test behavioral epigenetics in the nematode, Caenorhabditis elegans. We hypothesized that pre-exposure to an aversive pheromone, octopamine-succinylated ascaroside #9, would result in a change in the behavior observed upon sensation, and that this change would be seen across multiple generations. We show that pre-exposure results in a decrease in avoidance that is observed across three generations. Overall, the data exemplifies how nurture can later affect nature.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2018

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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