Faculty Advisor

Makarov, Sergey N.


Transcranial magnetic stimulation is a burgeoning field of medicine currently under study exploring its therapeutic and diagnostic applications. One such study at the Massachusetts General Hospital concerns a patient who had a seizure while undergoing TMS treatment for medication-resistant depression. The purpose of this Major Qualifying Project was to create an accurate model of the patient from T1 and T2 magnetic resonance imaging data using a complex toolchain of medical imaging and mesh processing software. ANSYS Maxwell was used to conduct a finite element analysis of the patient’s unique cranial geometry to calculate the electric field inside the cortex during a simulated TMS procedure. This analysis was done to gain insight into the cause of the patient’s seizure.


Worcester Polytechnic Institute

Date Accepted

April 2017


Electrical and Computer Engineering

Project Type

Major Qualifying Project



Advisor Department

Electrical and Computer Engineering