Understanding metastatic cancer cells is important to increasing the cancer survival rate. Microfluidic fabrication allows us to create diminutive environments to perform experiments on individual cells. This project was aimed at developing a design for a microfluidic device that has the potential to separate metastatic and non-metastatic cancer cells via chemotaxis through a hydrogel basement membrane mimic. The team’s device allows for the isolation and expansion of metastatic cancer cells within micron-sized wells for further analysis.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Petry, Stephen O.
• Maitland, Ian Maxwell
• Sundseth, Stuart Scott
• Haley, Connor Michael

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-043015-083231

Advisor

• Albrecht, Dirk
• Ambady, Sakthikumar

Year

• 2015

Date created

• 2015-04-30

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright