Faculty Advisor

Yu, Weiyong

Faculty Advisor

Zhou, Hong Susan

Abstract

Using electrical impedance spectroscopy, three nanoparticle-based detection schemes were investigated. In particular, reproducibility and ease of amplification were thoroughly analyzed. Though all three configurations successfully detected the presence of the target molecule (human IgE), the sensor utilizing an aptamer sandwich mechanism generated reproducible, large impedance changes in the presence of human IgE.

Publisher

Worcester Polytechnic Institute

Date Accepted

March 2010

Major

Chemistry

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemistry and Biochemistry

Advisor Department

Chemical Engineering

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