Student Work

Developing a Multiplexing Assay System for the Quality Control of Cell Therapy Products

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When used for autologous transplant, mesenchymal stem cells require extensive quality control (QC) before being reintroduced into the body. One standard method of QC is biological assays, which are laboratory tests for determining the concentration of foreign substances in a cell culture solution. Biological assays have a number of limitations including time, cost, and level of manual involvement. With these limitations in mind, a proof-of-concept device was developed to show the potential for an automated multiplexed assay device for QC. This prototype device design can accurately intake and dispense reagent volumes necessary for the completion of two assays. The device is also capable of providing the required temperature environment for each step of the assay process.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-042717-114121
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  • 2017
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Date created
  • 2017-04-27
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