Faculty Advisor
Krushkal, Julia S.
Faculty Advisor
Weathers, Pamela J.
Abstract
1-deoxy-D-xylulose-5 phosphate synthase (DXPS), a key regulatory enzyme in the nonmevalonate branch of the terpenoid biosynthetic pathway, is located in plastids. Sequence analysis of the DXPS and DXPS-like genes and signal sequences from multiple plant species included primary structure sequence alignments, common secondary structure features, and predicted hydrophobicity regions. The functional protein was found to be highly conserved, however the inferred gene trees did not resemble classical species trees. Although conservation of the signal sequence was not significant, there was similarity between hydrophobicity plots.
Publisher
Worcester Polytechnic Institute
Date Accepted
January 2001
Major
Biotechnology
Project Type
Major Qualifying Project
Copyright Statement
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Accessibility
Restricted-WPI community only
Advisor Department
Biology and Biotechnology