Faculty Advisor

Peura, Robert A.

Abstract

A potential non-invasive means for evaluating wound healing in vivo was investigated by characterizing the in-vitro bio-degradation of collagen sponges using MRI. Attempts to correlate measured MRI parameters with different degrees of collagen crosslinking were unsuccessful. Sodium alginate gels were also examined as a function of cross-linking (with Ca 2+) for alginate solutions of varying concentrations (0.18, 0.27, and 0.36M). The MRI-measured transverse relaxation rates and proton densities varied approximately linearly over this range of alginate concentrations.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2005

Major

International Studies

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biomedical Engineering

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