Politz, Samuel M.
A stage-specific switch of surface composition in Caenorhabditis elegans has been identified which is inducible by growth conditions. Wild-type worms grown in the presence of a crude pheromone extract do not switch off the epitope for the M37 monoclonal antibody between the L1 and L2 developmental stages. To determine what genes and cells are required for this inducible larval display of surface antigens, antibody staining with M37 was performed on chemosensory mutants. Results indicate that ciliated neurons are required.
Worcester Polytechnic Institute
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Biology and Biotechnology