Faculty Advisor

Politz, Samuel M.

Abstract

A stage-specific switch of surface composition in Caenorhabditis elegans has been identified which is inducible by growth conditions. Wild-type worms grown in the presence of a crude pheromone extract do not switch off the epitope for the M37 monoclonal antibody between the L1 and L2 developmental stages. To determine what genes and cells are required for this inducible larval display of surface antigens, antibody staining with M37 was performed on chemosensory mutants. Results indicate that ciliated neurons are required.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 1999

Major

Biology

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

Share

COinS