Faculty Advisor
Argüello, José M.
Abstract
Heavy metals are essential for the development and function of many organisms. One family of enzymes that transport metals, PIB-ATPases are found in organisms ranging from bacteria to humans. PIB-ATPases are classified into different subgroups dependent on the metal transported. Model enzymes from these different subgroups are needed to study these enzymes. This report focuses on the characterization of several PIB-ATPases and their applications as models for further studies. As a result of these studies, five possible models have been identified.
Publisher
Worcester Polytechnic Institute
Date Accepted
January 2006
Major
Biochemistry
Project Type
Major Qualifying Project
Copyright Statement
Access to this report is limited to members of the WPI community. Please contact a project advisor or their department to request access
Accessibility
Restricted-WPI community only
Advisor Department
Chemistry and Biochemistry