Faculty Advisor

Dittami, James P.

Abstract

Huperzine A and B, alkaloids isolated from the club moss Huperzia serrata, are employed in traditional Chinese medicine to treat senile dementia and other ailments. Previous attempts to synthesize Huperzine analogs relying on a heteroatom directed photoarylation reaction encountered difficulties when a pyridine ring system was incorporated into the photoprecursor. This research seeks to develop an alternative to photochemical initiation of the heteroatom directed arylation employing microwave radiation.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2004

Major

Chemistry

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Chemistry and Biochemistry

Advisor Program

Chemistry and Biochemistry

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