Faculty Advisor

Politz, Samuel M.

Abstract

In the free-living nematode C. elegans, srf-6 mutations affect the nematode's ability to change its surface-coat composition. Such changes may be crucial to the success of parasitic nematode infections. A previously identified candidate gene for srf-6 has been analyzed by sequencing of srf-6 mutant DNA to identify the mutant DNA sequence corresponding to the gene. In another aspect of the project, sequence similarities between the C. elegans srf-6 candidate and its ortholog in the related species C. briggsae were analyzed.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2004

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

Advisor Program

Biology and Biotechnology

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