Faculty Advisor

Krushkal, Julia S.

Faculty Advisor

Ruiz, Carolina

Faculty Advisor

Ryder, Elizabeth F.

Abstract

In this project, we used two data mining tools, CBA and WEKA, to search for genetic polymorphisms that affect two human diseases, autosomal recessive spinal muscular atrophy (SMA) and bilateral optic neuropathy (LHON). We modified WEKA to be able to mine genetic data. Our results provided a number of association rules, which identified important genetic variants and phenotypic factors affecting the disease state and severity.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2001

Major

Biology

Major

Computer Science

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

Advisor Department

Computer Science

Advisor Program

Biology and Biotechnology

Advisor Program

Computer Science

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