Faculty Advisor

Camesano, Terri A.

Abstract

Modified dextran polymers are used as surfactants in oil in water emulsions, and serve as a hydrophobic boundary layer between the oil droplet surface and its aqueous surroundings, allowing for the formation stable emulsions that consist of biocompatible materials, a possible vector for drug delivery for oil-based drugs. These emulsions consist of Nujol (mineral) oil and a hydrophobically modified destran polymer solution (DexC, DexC, or DexP). Polymer solution concentrations greater than 5 grams per liter allowed for emulsion stability over long periods of time. A combination of centrifugation and lyophilization was determined to be a viable method for storage. Research was performed in collaboration with WPI and ENSIC.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2002

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Chemical Engineering

Advisor Program

Chemical Engineering

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