Faculty Advisor

Politz, Samuel M.

Abstract

Nematode surface proteins share structural properties with vertebrate mucins. During infection, parasitic nematodes may change these surface proteins to escape host immune responses. Studies of the Caenorhabditis elegans srf-6 gene led to discovery of a mucin-like coding sequence called F41G3.10 The amino acid sequence encoded is similar to that of a know nematode surface protein. An RNA transcript of F41G3.10 was detected in wild type C. elegans RNA. Developmentally synchronous cultures will be studied to determine when F41G3.10 is expressed.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2001

Major

Biotechnology

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

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