Krushkal, Julia S.
Ryder, Elizabeth F.
One unanswered question is how the expression of genes is controlled. Using computational tools to discover patterns in DNA, the project team designed and implemented MEBCS, a data-mining software package able to classify the expression of a novel promoter sequence. MEBCS is capable of performing multipoint analysis on putative motifs, as discovered by the system, and constructs predictive models using prior expression information. These models were tested on a C. elegans dataset collected by the project team.
Worcester Polytechnic Institute
Major Qualifying Project
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Biology and Biotechnology