Faculty Advisor

Rulfs, Jill

Abstract

Past experimental data has suggested that some unknown growth factor expressed by adult but not young rat hepatocytes is responsible for arresting proliferation. To begin to identify this growth factor, this project utilizes a method recently pioneered by Clontech Laboratories called Suppression Subtractive Hybridization (SSH) to compare RNA sequences found in young and adult rat hepatocytes. Future projects will use the acquired data to eventually clone and identify the functional growth factor.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2001

Major

Biology

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

Advisor Program

Biology and Biotechnology

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