Faculty Advisor
Hobey, William D.
Abstract
Rab GTPases regulate vesicle trafficking in the cell and there are 37 functionally distinct members. This project began a molecular cloning library to facilitate a proteome wide quantitative analysis. This is the start of determining which RAB interactions are bona fide, which are not and give an insight into modes specificity. It will propel a structural study of Rab GTPases. This work clarifies a possible interaction between a Rab and an effector and shows the novel crystal structure of Rab33b.
Publisher
Worcester Polytechnic Institute
Date Accepted
January 2003
Major
Biochemistry
Project Type
Major Qualifying Project
Copyright Statement
Access to this report is limited to members of the WPI community. Please contact a project advisor or their department to request access
Accessibility
Restricted-WPI community only
Advisor Department
Chemistry and Biochemistry
Advisor Program
Chemistry and Biochemistry