Faculty Advisor

Adams, David S.

Center

UMMC / University of Massachusetts Medical Center

Abstract

Current neurological research indicates that the improper migration of neurons into subcortical white matter in humans may play a role in the etiology of schizophrenia, major depressive disorder, autism, and other psychological disorders. The purpose of this project was to isolate mRNA from both white and gray matter samples from mentally ill and healthy individuals in an effort to elucidate mRNA gene expression differences between white matter neurons and gray matter neurons, if any. These differences in gene expression may open new avenues of research and treatment in patients suffering from psychiatric disorders with genetic etiologies.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2012

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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