Faculty Advisor

Ryder, Elizabeth F.

Faculty Advisor

Ward, Matt

Abstract

SimCortex 2.0 was created as an interactive graphical simulation of the development of the cerebral cortex in the mouse. Progenitor proliferation, neuronal migration along glial fibers, and cell death are modeled. As the simulation progresses, radial glia defasciculate and transform morphologically, and neurons travel to their destined layers. The user can alter the simulated development by manipulating probabilistic processes to experiment with the results. Characteristics of cerebral development were successfully validated within the simulation when compared to current research data.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2000

Major

Biotechnology

Major

Computer Science

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

Advisor Department

Computer Science

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