Faculty Advisor

Lambert, Christopher R.

Faculty Advisor

Page, Raymond L.

Faculty Advisor

Rolle, Marsha W.

Abstract

Current tissue culture techniques lack the ability to position cells into 3-D shapes without an exogenous scaffold. The goal of the project was to design a bioreactor that positions cells in 3-D and supports tissue growth. Collagen-coated agarose beads seeded with rat aortic smooth muscle cells were introduced into the bioreactor and positioned on a magnetic rod, forming a tube. The device was run for five days without contamination and met the design objectives.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2010

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemistry and Biochemistry

Advisor Department

Biology and Biotechnology

Advisor Department

Biomedical Engineering

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