Despite technical advancements in radiation and chemotherapy, pancreatic cancer remains resistant to treatment, with poor survival rates. Using both cell and animal models, we investigated combined radiation and chemotherapy regimens for their effectiveness in reducing tumor growth. Preliminary data suggests combination therapy may be more efficacious than either therapy alone, reducing in vitro growth of a pancreatic cell line and in vivo tumor size. Markers of angiogenesis suggest combined treatment may also result in a reduction in tumor vasculature.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Wise, Jillian F

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-030107-161003

Advisor

• Rulfs, Jill

Year

• 2007

Sponsor

• Dr. Cheryl Baker

Date created

• 2007-03-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright