Faculty Advisor

Rulfs, Jill

Abstract

Despite technical advancements in radiation and chemotherapy, pancreatic cancer remains resistant to treatment, with poor survival rates. Using both cell and animal models, we investigated combined radiation and chemotherapy regimens for their effectiveness in reducing tumor growth. Preliminary data suggests combination therapy may be more efficacious than either therapy alone, reducing in vitro growth of a pancreatic cell line and in vivo tumor size. Markers of angiogenesis suggest combined treatment may also result in a reduction in tumor vasculature.

Publisher

Worcester Polytechnic Institute

Date Accepted

March 2007

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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