Crusberg, Theodore C.
Sisson, Richard D.
The purpose of this MQP was to determine whether WPI's nuclear reactor is suitable for Boron Neutron Capture Therapy. The research included neutron irradiation of cells from the L6 adherent cell line to ascertain if the neutrons required for this binary therapy were available at WPI. Cells were irradiated with and without infusion of boronophenylalanine (BPA). Using a neutron filter, composed of a gamma shield and moderating polyethylene, a neutron flux sufficient for BNCT was obtained. It was concluded that this neutron flux could be utilized in conjunction with boron compounds to perform to BNCT studies using the WPI nuclear reactor.
Worcester Polytechnic Institute
Major Qualifying Project
Access to this report is limited to members of the WPI community. Please contact a project advisor or their department to request access
Restricted-WPI community only
Biology and Biotechnology