Faculty Advisor

Pavlik, James W.

Abstract

The synthesis of 1,3,6-trimethyl-1H-pyrano [2,3-C]pyrazol-4one, 12 has been attempted. The initial steps involving the preparation of 1,3-dimethylpyrazolone 6 and C-acylation to yield 4-acetyl-5-hydroxy-1,3-dimethylpyrazole 9 were successfully carried out. Although the next step in the synthesis requires C-acylation of 9 at the methylketone side chain; only O-acylation was observed under a variety of conditions.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2003

Major

Chemistry

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Chemistry and Biochemistry

Advisor Program

Chemistry and Biochemistry

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