Faculty Advisor

Argüello, José M.

Abstract

The uses of informatics in chemical and biochemical research were explored. Two chemical database search tools, Beilstein Commander and SciFinder, were analyzed and laboratory manuals for each of these were developed. Two protein homology modeling programs, Cn3D and Deep View, were used to construct models for CopA, a Cu-ATPase based upon the known coordinates of SERCA, a Ca-ATPase. A reasonable CopA model that allows visualization of the residues involve in copper transport was produced.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2004

Major

Biochemistry

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Chemistry and Biochemistry

Advisor Program

Chemistry and Biochemistry

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