Ryder, Elizabeth F.
Boston University Medical School
This project examined the transcriptional regulation of the 2A adrenergic receptors in a central adrenergic cell line (CATH.a). The study suggests that cAMP induces the transcription of 2A gene in these cells. It is also consistent with the fact that the cAMP response element binding protein (CREB) is not involved in the basal transcription of the 2A gene. These results suggest the presence of a different basal transcription mechanism than the one used in other studied cell lines (RIN5mF).
Worcester Polytechnic Institute
Major Qualifying Project
Access to this report is limited to members of the WPI community. Please contact a project advisor or their department to request access
Restricted-WPI community only
Biology and Biotechnology