Faculty Advisor

Ryder, Elizabeth F.

Abstract

This project examined the transcriptional regulation of the 2A adrenergic receptors in a central adrenergic cell line (CATH.a). The study suggests that cAMP induces the transcription of 2A gene in these cells. It is also consistent with the fact that the cAMP response element binding protein (CREB) is not involved in the basal transcription of the 2A gene. These results suggest the presence of a different basal transcription mechanism than the one used in other studied cell lines (RIN5mF).

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2000

Major

Biotechnology

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Biology and Biotechnology

Advisor Program

Biology and Biotechnology

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