Faculty Advisor
Ryder, Elizabeth F.
Sponsor
Boston University Medical School
Abstract
This project examined the transcriptional regulation of the 2A adrenergic receptors in a central adrenergic cell line (CATH.a). The study suggests that cAMP induces the transcription of 2A gene in these cells. It is also consistent with the fact that the cAMP response element binding protein (CREB) is not involved in the basal transcription of the 2A gene. These results suggest the presence of a different basal transcription mechanism than the one used in other studied cell lines (RIN5mF).
Publisher
Worcester Polytechnic Institute
Date Accepted
January 2000
Major
Biotechnology
Project Type
Major Qualifying Project
Copyright Statement
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Accessibility
Restricted-WPI community only
Advisor Department
Biology and Biotechnology
Advisor Program
Biology and Biotechnology