During development in Caenorhabditis elegans (C.elegans), several neurons migrate to specific locations, within the body; this is important in the formation of the nervous system. Mutations in the mig-10 gene have been phenotypically identified by incomplete migration of those cells and the truncation of the excretory cell. This project focuses on identification of additional mutations in the gene, isolated by non-complementation screening, and characterized using PCR and restriction digestion. Missense mutations may identify functional domains in the MIG-10 protein.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• de Rham, Teresse Marion
• Zhang, Min
• LeBlanc, Katelyn A.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042108-201623

Advisor

• Rulfs, Jill
• Ryder, Elizabeth F.
• Buckholt, Michael Allan

Year

• 2008

Date created

• 2008-04-21

Resource type

• Major Qualifying Project

Major

• Biochemistry
• Biology & Biotechnology

Rights statement

• In Copyright

Last modified

• 2021-02-02