Student Work
A Simple Model for Analyzing Stem Cell Niches in Human Skin
PublicDownloadable Content
open in viewerEach year, millions of Americans require skin grafts. One promising approach is to use patient-derived epithelial stem cells to replace damaged skin. Micro-niches, which support epithelial stem cells, exist within the epidermis. To understand and bio-engineer these niches, a simple experimental platform must be developed. Using an existing basal lamina analogue that mimicked the topography of the dermal-epidermal junction I have developed an approach using optical sectioning fluorescent microscopy that allows for rapid characterization of functional perturbations to this system.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042611-170922
- Advisor
- Year
- 2011
- Date created
- 2011-04-26
- Resource type
- Major
- Rights statement
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- In Collection:
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Items
Thumbnail | Title | Visibility | Embargo Release Date | Actions |
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NAGLE-MQP-BIO-JBD-0008-A_Simple_Model_for_Analyzing_Stem_Cell_Niches_in_Human_Skin.pdf | Public | Download |
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