Faculty Advisor

Wobbe, Kristin K.

Abstract

Turnip crinkle virus protein p8 has been shown to cooperatively bind RNA in vitro. Current techniques for analyzing this protein/RNA interaction have inherent limitations, including time required to perform the assay and lack of quantitative data. Capillary electrophoresis (CE) was evaluated as a potential platform to overcome these shortcomings, ideally providing both rapid analysis and quantifiable data. Due to several complicating factors, a CE assay is shown to be too difficult to perform and analyze to be of practical value.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2000

Major

Biochemistry

Project Type

Major Qualifying Project

Accessibility

Restricted-WPI community only

Advisor Department

Chemistry and Biochemistry

Advisor Program

Chemistry and Biochemistry

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