Wobbe, Kristin K.
Using synthetic polymers, scaffolds can be created for tissue engineering. The goal of this project was to fabricate and evaluate porous PCL scaffolds for cartilage-tissue engineering. By varying molecular weight and porosity, scaffolds were ultimately designed for cell seeding. Three molecular weights were tested, as well as four different salt/polymer ratios. High molecular-weight scaffolds with a high salt/polymer ratio proved to be the most promising for in vitro growth of chondrocytes.
Worcester Polytechnic Institute
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Chemistry and Biochemistry