Gaudette, Glenn R.
DEKA Research and Development Corporation
Lack of a viable vascular network impedes 3D bioprinting from creating functional tissues. Utilizing the native vasculature of decellularized spinach leaves as a scaffold for cell seeding provides the potential to form a viable vascular network. This network coupled with a gel matrix has the potential to provide the support and nutrients necessary for printing functioning tissues. Our data shows cell viability within a seeded scaffold after 36 hours and demonstrates cellular escape from the spinach leaf scaffold. When combined, the data shows that cells have the ability to adhere and escape from the scaffold, into a gel matrix, mimicking the initial steps for vascular growth.
Worcester Polytechnic Institute
Major Qualifying Project
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