Page, Raymond L.
Engineered skeletal muscle tissue has the potential to aid in valuable research and treatment methods for a plethora of musculoskeletal disorders and injuries. While advances have been made in the past decade, diseases such as muscular dystrophy lack sufficient predictive disease models to facilitate trials of novel medicine, and current engineered tissues tend to lack vital characteristics of native tissue. This project thus focuses on one mechanism which has the potential to improve the traits of myoblasts cultured ex-vivo; mechanical stimulation. In the absence of a streamlined mechanical stimulation device, the goal of this MQP project was to design, prototype, and test such a device.
Worcester Polytechnic Institute
Major Qualifying Project
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