Faculty Advisor

Buckholt, Michael Allan

Faculty Advisor

Faber, Brenton

Faculty Advisor

Rulfs, Jill

Abstract

There is evidence that the over the counter postmenopausal phytoestrogen supplement, Promensil, has antiproliferative effects on cells of the T47D breast cancer cell line. This project aims to examine if the antiproliferative effects of Promensil on the T47D breast cancer cell line may be due to activation of caspase-3, causing apoptosis of the cells. To complement this project, a retrospective evaluation of comorbidities among 202 rural breast cancer patients was conducted. Data showed that their comorbidities are consistent with those identified in larger national studies and include hypertension, type 2 diabetes, high cholesterol, and cardiac history.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2019

Major

Interdisciplinary

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

Advisor Department

Humanities and Arts

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