Directed evolution is a powerful tool used to create improved proteins. Despite its promise, the growing complexity of directed evolution systems limits their transferability. This paper details a Bacterial Non-Continuous Evolution model (BaNCE) that aims to conserve the power of directed evolution while simplifying the process to make it accessible to a wider group of researchers. In addition to its design, experiments were performed to investigate the potential of this system and outline future steps for its development.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Andon, James S.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-051220-151436

Award

• Provost's MQP Award

Advisor

• Heilman, Destin

Year

• 2020

Date created

• 2020-05-12

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright

Last modified

• 2023-01-19