Directed evolution is a powerful tool used to create improved proteins. Despite its promise, the growing complexity of directed evolution systems limits their transferability. This paper details a Bacterial Non-Continuous Evolution model (BaNCE) that aims to conserve the power of directed evolution while simplifying the process to make it accessible to a wider group of researchers. In addition to its design, experiments were performed to investigate the potential of this system and outline future steps for its development.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry