Student Work

Design of a System for the Creation of Biaxially Aligned Fibrin Microthread Scaffolds for Cardiac Regeneration

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Fibrin microthread scaffolds have been researched for cardiac regeneration. The project goal was to design an automated scaffold production system that would achieve more consistent thread alignment and spacing than the current manual method. The system included a grooved suction alignment device, transfer frame, and final composite formation mold. Structural tests were performed to compare the thread spacing of the automated and manual scaffolds. Mechanical tests were used to compare the maximum load the scaffold samples could sustain. Statistical analyses confirmed the automated system achieved reproducible scaffold fabrication. Therefore, the system fabricates reproducibly aligned fibrin microthread composite scaffolds.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • E-project-043015-000843
Advisor
Year
  • 2015
Date created
  • 2015-04-30
Resource type
Major
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Last modified
  • 2021-02-01

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