The goal of this project is to design and implement a user-friendly machine learning tool that can be applied to the classification of polypeptides to find functional nuclear export sequences (NESs). This tool incorporates an API that takes advantage of support vector machines and can be expanded to include other models. Because NESs have been found to have consistent structure, structural data is incorporated into the model to increase confidence. This report is accompanied by a manual that instructs users on how to use the tool.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry