UMass Medical School
The exocyst complex plays roles in membrane trafficking and fusion during exocytosis. Current Cryo-EM models do not provide clear structural information on the complex or its CorEx bundles. CorEx bundles are involved in connecting the two exocyst modules, though the mechanism is poorly understood. We attempted to obtain a crystallized structure of a CorEx bundle by two methods: building the complex using a polycistronic plasmid system and digesting the complex by limited proteolysis.
Worcester Polytechnic Institute
Major Qualifying Project
All authors have granted to WPI a nonexclusive royalty-free license to distribute copies of the work, subject to other agreements. Copyright is held by the author or authors, with all rights reserved, unless otherwise noted.
Restricted-WPI community only
Chemistry and Biochemistry
Available for download on Thursday, May 18, 2023
Your accessibility may vary due to other restrictions.