Faculty Advisor

Manning, Amity L.

Faculty Advisor

Korkin, Dmitry

Abstract

This project seeks to understand the dynamics of DNA damage repair in cancerous cells utilizing preexisting software and novel analysis approaches. Current analysis tools allow biologists to independently track cell movement and count damage sites, but not simultaneously. Our methods identified a slight increase in damage frequency over time in motile cell populations. We suggest utilizing cell morphology rather than coordinate tracking for further advancements in this area.

Publisher

Worcester Polytechnic Institute

Date Accepted

2020-05-18

Major

Bioinformatics and Computational Biology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

Advisor Department

Computer Science

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