Faculty Advisor

Billiar, Kristen

Faculty Advisor

Gaudette, Glenn R.

Abstract

Human skin is constantly exposed to outside elements, making it one of the most vulnerable organs. Factors that contribute to deterioration of the skin’s appearance include disease, injury, and age. Cosmetics companies seek new developments to improve skin appearance. The team has discovered that fibrin, the body’s first responder protein in wound healing, can encapsulate retinol, a popular active ingredient used in cosmetics. Fibrin can be degraded by bromelain, a natural enzyme, to control the release of retinol. This demonstrates the opportunity for fibrin’s use as a carrier for cosmetic product ingredients. The team developed an automated process for producing fibrin microthreads infused with active ingredients, which were converted into particles, incorporated into a topical cream.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2017

Major

Mechanical Engineering

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biomedical Engineering

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